Bioactivity:GSK-J1 lithium salt is a potent inhibitor of me2-demethylases JMJD3/H3K27me3/KDM6B and UTX/KDM6A (IC50: 60 nM towards KDM6B).
CAS Nr:
T11475
Purity:
98%
SMILES:
[Li]OC(CCNC1=NC(C2=NC=CC=C2)=NC(N(CC3)CCC4=C3C=CC=C4)=C1)=O
Formula:
C22H22LiN5O2
Molecular weight:
395,38
Pathway:
Chromatin/Epigenetic
Target:
Histone Demethylase